124 cities and towns
| Abbreviation | 21 |
| State Population | 575,608 |
| # | City | Population | Median Income | Home Value | Median Rent | Median Age |
|---|---|---|---|---|---|---|
| 1 | Juliaca | 245,675 | N/A | N/A | N/A | 31.0 |
| 2 | Puno | 128,637 | N/A | N/A | N/A | 31.0 |
| 3 | La Rinconada | 29,678 | N/A | N/A | N/A | 31.0 |
| 4 | Ayaviri | 19,310 | N/A | N/A | N/A | 31.0 |
| 5 | Yunguyo | 16,140 | N/A | N/A | N/A | 31.0 |
| 6 | Ilave | 16,033 | N/A | N/A | N/A | 31.0 |
| 7 | Azángaro | 13,290 | N/A | N/A | N/A | 31.0 |
| 8 | Atuncolla | 12,654 | N/A | N/A | N/A | 31.0 |
| 9 | La Rinconada Ana Maria (La Rinconada) | 12,183 | N/A | N/A | N/A | 31.0 |
| 10 | Putina | 8,118 | N/A | N/A | N/A | 31.0 |
| 11 | Huancane | 7,831 | N/A | N/A | N/A | 31.0 |
| 12 | Juli | 7,309 | N/A | N/A | N/A | 31.0 |
| 13 | Macusani | 6,044 | N/A | N/A | N/A | 31.0 |
| 14 | Desaguadero | 5,329 | N/A | N/A | N/A | 31.0 |
| 15 | Lampa | 4,780 | N/A | N/A | N/A | 31.0 |
| 16 | Santa Lucía | 4,320 | N/A | N/A | N/A | 31.0 |
| 17 | Nuñoa | 4,271 | N/A | N/A | N/A | 31.0 |
| 18 | Sandia | 3,675 | N/A | N/A | N/A | 31.0 |
| 19 | Taquile | 2,000 | N/A | N/A | N/A | 31.0 |
| 20 | Vilavila | 990 | N/A | N/A | N/A | 31.0 |
| 21 | Palca | 969 | N/A | N/A | N/A | 31.0 |
| 22 | Arapa | 907 | N/A | N/A | N/A | 31.0 |
| 23 | Cabanilla | 895 | N/A | N/A | N/A | 31.0 |
| 24 | Chijichaya | 892 | N/A | N/A | N/A | 31.0 |
| 25 | Iguara | 877 | N/A | N/A | N/A | 31.0 |
| 26 | Mazo Cruz | 829 | N/A | N/A | N/A | 31.0 |
| 27 | Pusi | 828 | N/A | N/A | N/A | 31.0 |
| 28 | Cabana | 824 | N/A | N/A | N/A | 31.0 |
| 29 | Ocuviri | 823 | N/A | N/A | N/A | 31.0 |
| 30 | Huata | 823 | N/A | N/A | N/A | 31.0 |
| 31 | Sallacconi | 808 | N/A | N/A | N/A | 31.0 |
| 32 | Conima | 803 | N/A | N/A | N/A | 31.0 |
| 33 | Caracoto | 782 | N/A | N/A | N/A | 31.0 |
| 34 | Pilcuyo | 769 | N/A | N/A | N/A | 31.0 |
| 35 | Totoroma | 762 | N/A | N/A | N/A | 31.0 |
| 36 | Vilque | 731 | N/A | N/A | N/A | 31.0 |
| 37 | Tirapata | 691 | N/A | N/A | N/A | 31.0 |
| 38 | Esquena | 642 | N/A | N/A | N/A | 31.0 |
| 39 | Umachiri | 634 | N/A | N/A | N/A | 31.0 |
| 40 | Paucarcolla | 616 | N/A | N/A | N/A | 31.0 |
| 41 | Chingora | 595 | N/A | N/A | N/A | 31.0 |
| 42 | Pampa Yanamayo | 573 | N/A | N/A | N/A | 31.0 |
| 43 | Platería | 554 | N/A | N/A | N/A | 31.0 |
| 44 | Caritamaya | 540 | N/A | N/A | N/A | 31.0 |
| 45 | Capachica | 537 | N/A | N/A | N/A | 31.0 |
| 46 | Ticaraya | 525 | N/A | N/A | N/A | 31.0 |
| 47 | Vilque Chico | 511 | N/A | N/A | N/A | 31.0 |
| 48 | Chullune | 510 | N/A | N/A | N/A | 31.0 |
| 49 | Chimbo | 510 | N/A | N/A | N/A | 31.0 |
| 50 | Sihuayro | 506 | N/A | N/A | N/A | 31.0 |